The NanoPrint Microarray System is a robust and customizable platform for all microarray applications in Genomics, Proteomics and Diagnostics. The NanoPrint system manufactures high quality, precision microarrays utilizing the ArrayIt brand patented Stealth Micro Spotting Device, superior linear drive motion control technology, and proprietary Warp1 Servo controllers.  Compatible with all standard microarray surfaces (25 x 76 x 1mm), the system can easily be configured to print microarrays into the flat bottoms of 96 and 384 well plates by taking advantage of its flexible deck configuration and easy to use software interface.

The Stealth Micro Spotting Device is capable of printing DNA, RNA, cDNA, BACS, Oligonucleotides, Antibodies, Antigens, Proteins, Lipids, Carbohydrates, Receptors, Small Cells and many other biomolecules that can be put into suspension onto a solid surface.

Microarrays offer a technology for human disease screening, blood typing, parentage testing, forensics, human leukocyte antigen (HLA) analysis and infectious disease diagnosis.

Features

• A Method Creation Wizard
• User & Version Control Management
• Auto Calibration of the Slide and Microplate Positions
• Complete Sample Tracking
• Support of Input / Output Data Files
• Custom Array Designs
• Speed Profiles and Wash Protocols
• Automatic Method Validation
• Runtime Sample and Spotting Views
• Easy-to-use graphical Re-Print Function
• Software Simulation Mode

The high speed, high precision linear servo control system of the NanoPrint results in superior instrument performance in both speed and precision.  Combined with the efficient bench top design, user configurable worktable, humidity & dust control, host of available options and the flexible & sophisticated ArrayManager Software, the NanoPrint system is the complete solution for high performance microarray printing.

Benefits of linear drive technology

• Nanometer Scale Positional Accuracy
• Quiet Operation
• No Vibration
• No Heat Generation
• Superior Accuracy
• Maintenance Free
• High Speed
• High Load Capacity
• Zero "Sagging"
• Safety

NanoPrint Flexible Deck Configurations: Front left view of the NanoPrint™ showing three microplates, the wash/dry module and the printhead and pins printing onto glass substrates.  A 48-pin NanoPrint printhead loaded with 48 946 Micro Spotting Pins is printing location 8 on the deck.  The modular deck design and platen cassettes allow users to easily switch between glass substrates, microplates, wafers and other types of substrates.
Accessory Control Module (ACM): The ACM unit provides computer control for the wash/dry, humidity, and ultrasonication stations on the deck of the NanoPrint™.  The ACM unit fits neatly beneath the laboratory bench or under the optional anti-vibration table available with the system.  The ACM is extremely quiet and operates only as needed by the system.  Humidity is maintained in a user-specified manner of ±1%. Wash buffers are stored in carboys in front of the ACM.
NanoPrint™ Pin Cleaning Module: NanoPrint™ microarrayers are each equipped with a station that provides pin washing, drying and sonication of 1-48 pins.  The sonicator is automatically filled and emptied during the print run in a completely automated manner.  Systems sensors prevent splashing and overflowing for pin and deck safety. Drying is accomplished by vacuum using a quiet but powerful ACM-controlled function.  The Pin Cleaning Module is rugged, durable and easy to maintain.
NanoPrint™ ACM Connectivity: Easy connectivity between the ACM and the robot and accurate sensing of the humidity inside the chamber assures that proper humidity levels are achieved and maintained during the entire duration of each print run.  Dehumidification is an option available at an extra cost and is highly recommended for users who wish to operate their systems in humid environments.  The humidification and dehumidification systems are triggered by sensors that automatically maintain the levels set by the user.
NanoPrint™ Humidity Sensing: Accurate sensing of the humidity inside the chamber assures that proper humidity levels are achieved and maintained during the entire duration of each print run.  Dehumidification is an option available at an extra cost and is highly recommended for users who wish to operate their systems in humid environments.  The humidification and dehumidification systems are triggered by the RH sensor that automatically maintain the levels set by the user.
NanoPrint™ Microplate Peltier Cooling: NanoPrint™ systems offer sophisticated microplate cooling via Peltier as an affordable and highly recommended option for users wishing to minimize sample evaporation during printing. Microplate cooling is also highly recommended for protein microarray applications to minimize protein denaturation and microbial growth in recombinant protein samples.  The Peltier module fits directly beneath the microplate for highly efficient cooling while maintaining a low deck profile.
NanoPrint™ Software: The extraordinary and highly intuitive graphical user interface provides users with software writing speed, power and flexibility.  Shown here is a screen shot of the interstitial printing software command that automatically directs the robot to deposit the printed spots into a “orange packing” configuration for dramatically increased microarray printing densit
48 and 192 Pin Configurations are now available.  192 Pin configuration allows the user to run from 1 to 192 pins at 2.25 mm center to center spacing to pickup samples from 1536 well plates. Standard deliverable is 48 pins at 4.5mm centers for use with 384 well plates (96 well plates can also be configured). NanoPrint software and unique Pin and Printhead design allows the end user to setup the pin tool any way that they like. Multiplex array processing systems, plates, biochips micro fluidics, and cartridges can all be easily configured.
Superior Z-Axis Resolution for Optimum Spot Morphology: The Z-axis encoder on the NanoPrint™ reads at 250-nanometer resolution. Unlike belt and stepper motor driven Z-axis motion control, the NanoPrint™ offers highly precise resolution, repeatability and computer control over the speed and acceleration settings to ensure optimal printing onto any surface using our patented contact printing technology.  Optimal parameters are set at the factory but can be easily changed by the user for printing onto many different surfaces.